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Table 3 Diagnostic performance for acute posterior stroke absence or presence diagnosed with an incremental stroke protocol

From: The predictive value of a targeted posterior fossa multimodal stroke protocol for the diagnosis of acute posterior ischemic stroke

  Sensitivity (Se) Specificity (Sp)
Se % (95 % CI) p-value* Sp % (95 % CI) p-value*
Ischemia/ Infarct absent (Level of confidence score 5 and 6)
(1) NCCT 41.4 (32.9–50.0) (1) vs. (2): 0.103 83.7 (80.0–87.4) (1) vs. (2): < 0.0001
(2) NCCT + CTA-SI 52.3 (43.3–61.2) (1) vs. (3): 0.0007 95.7 (93.8–97.6) (1) vs. (3): < 0.0001
(3) NCCT+ CTA-SI + CTP 64.9 (55.7–74.0) (2) vs. (3): 0.072 92.8 (90.4–95.2) (2) vs. (3): 0.188
Infarct present (Level of confidence score ≤ 2 vs. > 2)
(1) NCCT 28.8 (20.6–37.1) (1) vs. (2): 0.032 91.5 (88.5–94.4) (1) vs. (2): < 0.0001
(2) NCCT+ CTA-SI 43.2 (33.9–52.6) (1) vs. (3): < 0.0001 97.7 (96.4–98.9) (1) vs. (3): 0.002
(3) NCCT+ CTA-SI + CTP 59.0 (49.3–68.7) (2) vs. (3): 0.025 96.1 (94.2–98.0) (2) vs. (3): 0.318
  1. NCCT non-contrast CT, CTA-SI CTA Source Images, CTP CT perfusion
  2. *p-value was obtained by linear regression model of natural log(Se) or log(Sp) for each modality