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Table 3 Diagnostic performance for acute posterior stroke absence or presence diagnosed with an incremental stroke protocol

From: The predictive value of a targeted posterior fossa multimodal stroke protocol for the diagnosis of acute posterior ischemic stroke

 

Sensitivity (Se)

Specificity (Sp)

Se % (95 % CI)

p-value*

Sp % (95 % CI)

p-value*

Ischemia/ Infarct absent (Level of confidence score 5 and 6)

(1) NCCT

41.4 (32.9–50.0)

(1) vs. (2): 0.103

83.7 (80.0–87.4)

(1) vs. (2): < 0.0001

(2) NCCT + CTA-SI

52.3 (43.3–61.2)

(1) vs. (3): 0.0007

95.7 (93.8–97.6)

(1) vs. (3): < 0.0001

(3) NCCT+ CTA-SI + CTP

64.9 (55.7–74.0)

(2) vs. (3): 0.072

92.8 (90.4–95.2)

(2) vs. (3): 0.188

Infarct present (Level of confidence score ≤ 2 vs. > 2)

(1) NCCT

28.8 (20.6–37.1)

(1) vs. (2): 0.032

91.5 (88.5–94.4)

(1) vs. (2): < 0.0001

(2) NCCT+ CTA-SI

43.2 (33.9–52.6)

(1) vs. (3): < 0.0001

97.7 (96.4–98.9)

(1) vs. (3): 0.002

(3) NCCT+ CTA-SI + CTP

59.0 (49.3–68.7)

(2) vs. (3): 0.025

96.1 (94.2–98.0)

(2) vs. (3): 0.318

  1. NCCT non-contrast CT, CTA-SI CTA Source Images, CTP CT perfusion
  2. *p-value was obtained by linear regression model of natural log(Se) or log(Sp) for each modality