Table 4 Outcomes
From: An historical and contemporary review of endovascular therapy for acute ischemic stroke
Recanalization (%, EVT v control) | Reperfusion (mTICI 2b/3, %) | Primary outcome | mRS at day 90 | mRS 0-2 at day 90 | Final infarct volume (mL) | sICH (PH-2, %) | Death at day 90 (%) | New AIS in a different territory (%) | SAE (%) | |
|---|---|---|---|---|---|---|---|---|---|---|
MR RESCUE | 69 | 27 | mRS 3.8 v 3.4 | 3.8 v 3.4 | 21 v 26 | 32 v 32 | 9 v 6 | 18 v 21 | 1.4 | 62 |
IMS III | 81 ICA; 86 M1; 88 M2 | 38 ICA; 44 M1; 44 M2 | mRS 0-2 41 v 39% | nr | 41 v 39 | nr | 6 v 6 | 19 v 21 | nr | nr |
SYNTHESIS | nr | nr | mRS 0-1 30 v 35% | nr | 42 v 46 | nr | 6 v 6 | 8 v 6 | nr | nr |
PISTE | 69 | 87 | OR 2.12 mRS 0-2 p = 0.2 | nr | 51 ϖ 40 νσ NNT = 9 | nr | 0 v 0 | 7 v 4 | nr | 45 v 34 |
THERAPY | nr | 70 | mRS 0-2 38 v 30% p = 0.44 | nr | 38 v 30 ns | nr | 9.3 v. 9.7 | 12 v 24 | nr | 42 v 48 |
MR CLEAN | 75 v 33 | 59 | mRS 3v4 day 90 | 3 v 4 | 33 v 19 NNT = 7 | 49 v 79 | 6 v 5 | 21 v 22 | 5.6 | 47 v 42 |
ESCAPE | nr v 31 (mAOL 2-3) | 72 | cOR 2.6 | 2 v 4 | 53 v 29 NNT = 4 | nr | 4 v 3 | 10 v 19 (significant) | nr | 21 v 18 |
EXTEND_IA | 94 v 43 (TIMI 2-3) | 86 | 24 hr reperfusion 100 v 37% Early neurological recovery 82 v 37% | 1 v 3 | 71 v 40 NNT = 3 | 23 v 53 | 0 v 6 | 9 v 20 (p = 0.18) | 5.7 | nr |
SWIFT PRIME | nr | 88 | Shift analysis p = 0.0002 | 2 v 3 | 60 v 36 NNT = 4 | nr | 1 v 3 | 9 v 12 (p = 0.5) | nr | 36 v 31 |
REVASCAT | nr | 66 | cOR 1.7 | nr | 44 v 28 NNT = 6 | 16 v 39 | 5 v 2 | 18 v 16 | 5 | 30 v 25 |
THRACE | 78 | 69 | mRS 0-2 at day 90 53v42% | nr | 53 v 42 NNT =9 | nr | 2 v 2 | 12 v 13 | 6 | 8 v 7 |